FITC标记的G蛋白偶联受体GPR78蛋白抗体
产品名称： FITC标记的G蛋白偶联受体GPR78蛋白抗体
英文名称： Anti-GPR78/FITC
产品编号： HZ-15363R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GPR78/FITC Conjugated antibody
| FITC标记的G蛋白偶联受体GPR78蛋白抗体 |
| 英文名称 | Anti-GPR78/FITC |
| 中文名称 | FITC标记的G蛋白偶联受体GPR78蛋白抗体 |
| 别 名 | GPCR GPR78; G-protein coupled receptor 78; GPR78; UNQ5925/PRO19818; GPR78_HUMAN; GPCR 78. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR78 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011] Function: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 27201 Human Omim: 606921 Human SwissProt: Q96P69 Human Unigene: 350588 Human Unigene: 740355 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码的蛋白属于G蛋白偶联受体家族，包含7个跨膜结构域，通过异源G蛋白转导细胞外信号。这是一个孤儿受体，显示显著水平的组成性活动。关联分析显示该基因参与双相情感障碍和精神分裂易感性的初步证据。另一种剪接转录变体已经发现这个基因。[ RefSeq，2011月11日]