FITC标记的胚胎干细胞关键蛋白190抗体(N端)
产品名称: FITC标记的胚胎干细胞关键蛋白190抗体(N端)
英文名称: Anti-Oct-4B(OCT4B-190)NT/FITC
产品编号: HZ-3816R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: Flow-Cyt=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-Oct-4B(OCT4B-190)NT/FITC Conjugated antibody
FITC标记的胚胎干细胞关键蛋白190抗体(N端)
英文名称 | Anti-Oct-4B(OCT4B-190)NT/FITC |
中文名称 | FITC标记的胚胎干细胞关键蛋白190抗体(N端) |
别 名 | Oct-4B; Oct4B; Oct 4B; Oct 4B-190; Oct4B-190; POU domain, class 5, transcription factor 1; Octamer-binding transcription factor 3; Oct-3; NF-A3; Otf-3; Otf3; POU5F1. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 干细胞 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, |
产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 21/39kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human OCT4B-190(NT) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]. Database links: Entrez Gene: 5460 Human Entrez Gene: 18999 Mouse Entrez Gene: 294562 Rat Omim: 164177 Human SwissProt: Q01860 Human SwissProt: P20263 Mouse Unigene: 249184 Human Unigene: 632482 Human Unigene: 646545 Human Unigene: 17031 Mouse Unigene: 161748 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OCT4B-190蛋白能够增强细胞在应激条件下抵抗凋亡的能力。OCT4基因在干细胞的增殖、分化、应激反应、凋亡过程等多个生物学过程中发挥着重要的作用 |
该基因编码含有pOH同源结构域的转录因子。该转录因子在胚胎发育中起重要作用,特别是在胚胎早期发育过程中,胚胎干细胞的多能性是必需的。该基因与尤文肉瘤基因T(6;22)(p21;q12)的易位,已与肿瘤形成有关。选择性剪接,以及替代翻译起始密码子的使用,导致多个异构体,其中一个起始于非AUG(CUG)起始密码子。在1, 3, 8、10和12染色体上已鉴定出相关的假基因。[由RefSeq提供]。