FITC标记的细胞毒性受体NK-p80抗体
产品名称: FITC标记的细胞毒性受体NK-p80抗体
英文名称: Anti-NKp80/FITC
产品编号: HZ-2681R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-NKp80/FITC Conjugated antibody
FITC标记的细胞毒性受体NK-p80抗体
英文名称 | Anti-NKp80/FITC |
中文名称 | FITC标记的细胞毒性受体NK-p80抗体 |
别 名 | C type lectin domain family 5 member C; CLEC5C; killer cell lectin like receptor F1; Killer cell lectin like receptor subfamily F member 1; KLRF 1; Lectin like receptor F1; MGC119907; MGC119908; MGC119909; ML; NKp80; KLRF1_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 免疫学 自然杀伤细胞 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 27kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human KLRF1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] Function: Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts. Subunit: Homodimer. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 51348 Human Omim: 605029 Human SwissProt: Q9NZS2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
KLF1是一种活化的同源二聚体C型凝集素样受体(CTLR),在几乎所有的自然杀伤(NK)细胞上表达,并刺激其细胞毒性和细胞因子释放(Kuttruffet等,2009 [PubMed 18922855 ])。