FITC标记的釉基质蛋白抗体
产品名称： FITC标记的釉基质蛋白抗体
英文名称： Anti-AMBN/FITC
产品编号： HZ-12467R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-AMBN/FITC Conjugated antibody
FITC标记的釉基质蛋白抗体
| 英文名称 | Anti-AMBN/FITC |
| 中文名称 | FITC标记的釉基质蛋白抗体 |
| 别 名 | AMBN; AMBN_HUMAN; Ameloblastin (enamel matrix protein); Ameloblastin. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞骨架 细胞外基质 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 45kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AMBN |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Dental enamel is a highly mineralized tissue with most of its volume occupied by large, highly organized, hydroxyapatite crystals. This structure is thought to be controlled through the interaction of many organic matrix molecules including amelogenin, ameloblastin, enamelin, tuftelin and several other enzymes. All of these secreted proteins are involved in the mineralization and enamel matrix formation in developing tooth enamel. Ameloblastin (AMBN), which localizes to the extracellular matrix, is an ameloblast-specific protein. It is detected in the sheath space between rod-interrod enamel and at the Tomes processes of secretory ameloblasts. Defects in the gene encoding for ameloblastin, AMBN, can be seen in patients with ameloblastomas. Function: Involved in the mineralization and structural organization of enamel. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel. Similarity: Belongs to the ameloblastin family. Database links: Entrez Gene: 258 Human Omim: 601259 Human SwissProt: Q9NP70 Human Unigene: 272396 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
牙釉质是高度矿化的组织，其体积的大部分由大型，高度组织，羟基磷灰石晶体占据。这种结构被认为是通过许多有机基质分子之间的相互作用来控制的，这些有机基质分子包括釉原蛋白、成釉细胞、珐琅质、簇绒蛋白和其他几种酶。所有这些分泌蛋白参与牙釉质的矿化和釉质基质的形成。Ameloblastin（AMBN），定位于细胞外基质，是成釉细胞特异性蛋白。在棒间釉的鞘空间和分泌成釉细胞的TIMES过程中检测到。在成釉细胞瘤患者中可见到编码成釉细胞蛋白（AMBN）的基因缺陷。