FITC标记的钾离子通道蛋白Kir7.1抗体
产品名称： FITC标记的钾离子通道蛋白Kir7.1抗体
英文名称： Anti-Kir7.1/FITC
产品编号： HZ-17074R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-Kir7.1/FITC Conjugated antibody
FITC标记的钾离子通道蛋白Kir7.1抗体
| 英文名称 | Anti-Kir7.1/FITC |
| 中文名称 | FITC标记的钾离子通道蛋白Kir7.1抗体 |
| 别 名 | Inward rectifier K(+) channel Kir7.1; Inward rectifier potassium channel 13; inwardly rectifying subfamily J member 13; IRK13_HUMAN; KCNJ13; KIR1.4; KIR7.1; LCA16; Potassium channel; Potassium inwardly rectifying channel subfamily J member 13; SVD. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 通道蛋白 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Dog, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 41kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Kir7.1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in this gene are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] Function: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium. Subcellular Location: Membrane. Tissue Specificity: Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord. DISEASE: Defects in KCNJ13 are the cause of snowflake vitreoretinal degeneration (SVD) [MIM:193230]. SVD is a developmental and progressive hereditary eye disorder that affects multiple tissues within the eye. Diagnostic features of SVD include fibrillar degeneration of the vitreous humor, early-onset cataract, minute crystalline deposits in the neurosensory retina, and retinal detachment. Similarity: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ13 subfamily. Database links: Entrez Gene: 3769 Human Entrez Gene: 100040591 Mouse Entrez Gene: 94341 Rat Omim: 603208 Human SwissProt: O60928 Human SwissProt: P86046 Mouse SwissProt: O70617 Rat Unigene: 467338 Human Unigene: 443539 Mouse Unigene: 14516 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码蛋白质内向整流钾通道家族的成员。这个家族的成员形成离子通道孔，允许钾离子进入细胞。该编码蛋白属于低信号传导蛋白亚家族，对钾浓度依赖性低。该基因突变与雪花玻璃体视网膜变性有关。交替剪接导致多个转录变异体。[ RefSeq，FEB 2010 ]提供