FITC标记的生物钟蛋白3抗体
产品名称: FITC标记的生物钟蛋白3抗体
英文名称: Anti-PER-3/FITC
产品编号: HZ-4498R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PER-3/FITC Conjugated antibody
FITC标记的生物钟蛋白3抗体
英文名称 | Anti-PER-3/FITC |
中文名称 | FITC标记的生物钟蛋白3抗体 |
别 名 | 2810049O06Rik; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; HGNC:8847; hPER3; mPer3; Per3; PER3_HUMAN; Period circadian protein homolog 3; Period homolog 3 (Drosophila); Period homolog 3; Period homolog 3, Drosophila; Period3. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 心血管 细胞生物 细胞周期蛋白 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 132kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PER-3 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. [provided by RefSeq, Jul 2008] Function: Component of the circadian clock mechanism which is essential for generating circadian rhythms. Can bind heme. Subcellular Location: Cytoplasm. Nucleus. Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS. Post-translational modifications: Phosphorylation appears to require association with PER1 and translocation to the nucleus. Ubiquitinated. Similarity: Contains 1 PAC (PAS-associated C-terminal) domain. Contains 2 PAS (PER-ARNT-SIM) domains. Database links: Entrez Gene: 8863 Human Entrez Gene: 18628 Mouse Entrez Gene: 78962 Rat Omim: 603427 Human SwissProt: P56645 Human SwissProt: O70361 Mouse SwissProt: Q8CJE2 Rat Unigene: 162200 Human Unigene: 121361 Mouse Unigene: 230006 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是周期基因家族的成员,在哺乳动物大脑中主要的昼夜节律起搏器——视交叉上核中以昼夜节律模式表达。这个家族的基因编码运动活动、新陈代谢和行为的昼夜节律的组成部分。视交叉上核中的昼夜节律表达在恒定的黑暗中持续,并且光/暗周期的变化引起视交叉上核中基因表达的比例变化。该基因的具体功能尚不清楚。[ RefSeq,JUL 2008 ]